Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Effect of peritoneal lavage in elective colorectal surgery: a randomised trial

ABSTRACT: Interventions: perform the paritoneal lavage with 3,000ml of warm saline not perform the peritoneal lavage Primary outcome(s): rate of SSI Study Design: Parallel Randomized

DISEASE(S): Colorectal Cancer

PROVIDER: 2620410 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

ACCESS DATA

Json Xml

Similar Datasets

Effect of Peritoneal Lavage With Clindamycin-Gentamicin Solution & Oncologic Outcome

Project description:Antibiotic lavage reduces bacterial contamination and decreases SSI infection rate. SSI leads to an immunocompromised situation, leaving unattended the neoplasm. It has been described that SSI may result in a worse oncologic outcome.

| 2186565 | ecrin-mdr-crc

Transcriptome profile of peritoneal lavage in response to adjuvants Alum and the polysaccharide from the roots of Actinidia eriantha (AEPS)

Project description:Analysis of peritoneal lavage from BALB/c mice 2 hours after intraperitoneal injection with PBS, AEPS, OVA, OVA+AEPS, or OVA+Alum. Results provide insight to explore the potential role of mRNAs and lncRNAs in adjuvant-induced innate immune response.

2021-01-31 | GSE124938 | GEO

Normal Equine BALF Proteomics - Functional modelling of an equine bronchoalveolar lavage fluid proteome provides experimental confirmation and functional annotation of equine genome sequences

Project description:Bronchoalveolar lavage fluid was collected from three clinically normal horses by infusing 300 ml of warm saline through a 300 cm foley catheter that was passed through the nasal passage into a terminal bronchus of the lung. BALF was retrieved by manual aspiration using a 60 cc syringe, placed immediately on ice, transported to the laboratory, and centrifuged (600xg 10 minutes 4oC). Aliquots of cell free BALF supernatant were frozen at -80C for subsequent proteomic analysis. Proteomic analysis was performed using a composite sample consisting of 100 g of BALF protein from each of three horses. Triplicate aliquots of the composite (75 g of protein each) were subjected to proteomic analysis as described (McCarthy et al. 2006) except that we did not perform differential detergent fractionation and we used one dimensional liquid chromatography (1D LC) nanospray ionization and not electrospray ionization.

2012-05-27 | PRD000303 | Pride

microRNA in mouse peritoneal tissue

Project description:Analysis of microRNAs in peritoneal tissues from mice treated with peritoneal dialysis fluid and saline

2019-05-03 | GSE130387 | GEO

Prospective study about Prophylactic resection of target organs of peritoneal metastasis and extensive peritoneal lavage for high-risk colorectal cancer

Project description:Interventions: experiment group:resection of target organs of peritoneal carcinomatosis combined with extensive intraperitoneal lavage Primary outcome(s): 3 year-peritoneal free survival Study Design: Single arm

| 2691111 | ecrin-mdr-crc

Transcriptome of isolated mouse peritoneal endothelial cells

Project description:To characterize the metabolic profile of peritoneal endothelial cells (ECs) in response to peritoneal dialysis (PD), we performed RNA sequencing of peritoneal ECs isolated from mice treated with PD fluid for 6 weeks (n = 3) and from mice treated with saline for 6 weeks (n = 3). We demonstrated that peritoneal ECs had a hyperglycolytic metabolism in response to PD fluid treatment, which is associated with the development of microvascular alterations and peritoneal dysfunction.

2023-12-06 | GSE230008 | GEO

Gene expression profile (RNAseq) of peritoneal mouse macrophages in Endotoxic shock and Tolerance

Project description:Purpose: Characterize the gene expression profile of of peritoneal mouse macrophages in Endotoxic shock and Tolerance through RNA sequencing Methods: RNA sequencing of RNA from peritoneal macrophages in Endotoxic shock and Tolerance isolated by peritoneal lavage and FACS sorting (F4/80+ CD11b+) Results: Endotoxic shock and Tolerance peritoneal mouse macrophages display differential gene expression. Conclusions: Endotoxic shock and Tolerance peritoneal mouse macrophages display differential gene expression.

2023-09-13 | GSE207328 | GEO

Temporal response of mouse peritoneal cells to a non-pathogenic E. coli infection

Project description:Analysis of early and late changes in the mouse peritoneal cells in response to E. coli induced sepis. Result provide an insight into the molecular function and pathways expressed at these different time points. The mice were divided in two groups; the first group of mice were not treated with E. coli and was referred to as the naive group. Each mouse of the second group was injected with 2 X108 cells of a non- pathogenic isolate of E. coli suspended in a phosphate buffered saline (PBS) solution. After 1h, 2h and 18h of E. coli administration, peritoneal lavage fluid was obtained from two mice each for E. coli treated group at 1 and 2h and three mice of both groups (control and E. coli treated) at 18h. A common naive group of 2 mice harvested at 2h served as a control for both 1h and 2h.

2012-12-30 | E-GEOD-34114 | biostudies-arrayexpress

Gene expression profile (RNAseq) of wild-type and Zeb1 (+/-) peritoneal mouse macrophages

Project description:Purpose: Characterize the gene expression profile of wild-type and Zeb1 (+/-) peritoneal mouse macrophages through RNA sequencing Methods: RNA sequencing of RNA from peritoneal macrophages isolated by peritoneal lavage and FACS sorting (F4/80+ CD11b+) from wild-type and Zeb1 (+/-) mice (2 mice pooled for each sample/set) Results: Wild-type and Zeb1 (+/-) peritoneal mouse macrophages display differential gene expression. Zeb1 (+/-) peritoneal macrophages express lower levels of SPM (F4/80low)-associated genes Conclusions: Wild-type and Zeb1 (+/-) peritoneal mouse macrophages display differential gene expression. Zeb1 (+/-) peritoneal macrophages express lower levels of SPM (F4/80low)-associated genes

2019-05-24 | GSE103830 | GEO