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Application and clinical trial of luminal nanosheets in colorectal cancer

ABSTRACT: Interventions: LDH/EDTA:Colorectal perfusion Primary outcome(s): Fecal occult blood test;Blood RT;Liver function and renal function;Tumor markers detection Study Design: Single arm

DISEASE(S): Colorectal Cancer

PROVIDER: 40615 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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Leukocyte accumulation in graft blood vessels during self-limiting acute rejection of rat kidneys Immunobiology

Project description:Acute rejection episodes trigger chronic renal allograft vasculopathy. Numerous leukocytes, predominantly monocytes, accumulate in graft blood vessels during reversible acute rejection preceding chronic rejection of rat kidneys. We speculate that they contribute to transplant vasculopathy and set out to characterize them. Allogeneic renal transplantation was performed in the Fischer 344 to Lewis rat strain combination, Lewis isografts served as controls. Leukocytes were harvested by intensive perfusion of graft blood vessels and subjected to flow cytometry, quantitative RT-PCR and genome-wide transcriptional profiling.

2010-09-24 | GSE18266 | GEO

Clinical research and the mechanism of Cinobufotalin combination chemotherapy prevent the relapse and metastasis of colorectal cancer

Project description:Interventions: Trial group :Cinobufotalin combination chemotherapy ;Control:Chemotherapy Primary outcome(s): routine blood test;Urine routine test;Fecal routine test;Fecal occult blood;Liver and kidney function;Immune functionCD3?CD4;Tumor markers CA199, CEA, CA50, CA125;TCM Syndrome Rating Scale;Piper Fatigue Scale Study Design: Randomized parallel controlled trial

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Leukocyte accumulation in graft blood vessels during self-limiting acute rejection of rat kidneys Immunobiology

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Metabolomics Workbench ST000342 - GNPS - Renal metabolic pathways indicating ischemic or inflammatory changes

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First approach on the use of samples from fecal occult blood screening kits for metabolomic analysis. Application in colorectal cancer population.

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Renal metabolic pathways indicating ischemic or inflammatory changes

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