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Beta cell transcriptome UNIGE

ABSTRACT: Data Access Committee EGAC00001000101

PROVIDER: EGAC00001000101 | EGA |

REPOSITORIES: EGA

ACCESS DATA

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Publications

Analysis artefacts of the INS-IGF2 fusion transcript.

Wernersson Rasmus R Frogne Thomas T Rescan Claude C Hansson Lena L Bruun Christine C Grønborg Mads M Jensen Jan Nygaard JN Madsen Ole Dragsbæk OD

BMC molecular biology 20150729

<h4>Background</h4>In gene expression analysis, overlapping genes, splice variants, and fusion transcripts are potential sources of data analysis artefacts, depending on how the observed intensity is assigned to one, or more genes. We here exemplify this by an in-depth analysis of the INS-IGF2 fusion transcript, which has recently been reported to be among the highest expressed transcripts in human pancreatic beta cells and its protein indicated as a novel autoantigen in Type 1 Diabetes.<h4>Resu ...[more]

PMID: 26220792

Publication: 1/2

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