Dataset Information
Wellcome Trust Sanger Institute Data Sharing Policy for Trachoma GWAS
Ontology highlight
ABSTRACT:
PROVIDER: EGAC00001000489 | EGA |
REPOSITORIES: EGA
Publications
Conjunctival fibrosis and the innate barriers to Chlamydia trachomatis intracellular infection: a genome wide association study.
Scientific reports 20151130
Chlamydia trachomatis causes both trachoma and sexually transmitted infections. These diseases have similar pathology and potentially similar genetic predisposing factors. We aimed to identify polymorphisms and pathways associated with pathological sequelae of ocular Chlamydia trachomatis infections in The Gambia. We report a discovery phase genome-wide association study (GWAS) of scarring trachoma (1090 cases, 1531 controls) that identified 27 SNPs with strong, but not genome-wide significant, ...[more]
