Genomics

Dataset Information

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Data access committee (DAC) in the Graduate School of Medical Science and Engineering (GSMSE) at Korea Advanced Institute of Science and Technology (KAIST)


ABSTRACT: Data Access Committee EGAC00001000587

PROVIDER: EGAC00001000587 | EGA |

REPOSITORIES: EGA

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Publications

Complex chromosomal rearrangements by single catastrophic pathogenesis in NUT midline carcinoma.

Lee J-K JK   Louzada S S   An Y Y   Kim S Y SY   Kim S S   Youk J J   Park S S   Koo S H SH   Keam B B   Jeon Y K YK   Ku J-L JL   Yang F F   Kim T M TM   Ju Y S YS  

Annals of oncology : official journal of the European Society for Medical Oncology 20170401 4


<h4>Background</h4>Nuclear protein in testis (NUT) midline carcinoma (NMC) is a rare aggressive malignancy often occurring in the tissues of midline anatomical structures. Except for the pathognomonic BRD3/4-NUT rearrangement, the comprehensive landscape of genomic alterations in NMCs has been unexplored.<h4>Patients and methods</h4>We investigated three NMC cases, including two newly diagnosed NMC patients in Seoul National University Hospital, and a previously reported cell line (Ty-82). Whole  ...[more]

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