Dataset Information
RNA-SEQ_DATA_SET_rain_PA_2012_10_22 - samples
Ontology highlight
ABSTRACT:
PROVIDER: EGAD00001000617 | EGA |
REPOSITORIES: EGA
Publications
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma.
Nature genetics 20130630 8
Pilocytic astrocytoma, the most common childhood brain tumor, is typically associated with mitogen-activated protein kinase (MAPK) pathway alterations. Surgically inaccessible midline tumors are therapeutically challenging, showing sustained tendency for progression and often becoming a chronic disease with substantial morbidities. Here we describe whole-genome sequencing of 96 pilocytic astrocytomas, with matched RNA sequencing (n = 73), conducted by the International Cancer Genome Consortium ( ...[more]
