EGAS00001001675-sc-20170705 - samples
Ontology highlight
ABSTRACT: A EGFR mutant NSCLC cell line which is sensitive to AZD9291 inhibition was mutagenised with the chemical mutagen ENU and then drug selected using a AZD9291. Single cell derived colonies were then manually picked and expanded in drug. Resistance was confirmed in a 14 day assay and DNA was collected. These then underwent targeted amplicon-based sequencing to confirm candidate resistance effectors hypothesised from currently available literature.
This dataset contains all the data available for this study on 2017-07-05.
PROVIDER: EGAD00001003425 | EGA |
REPOSITORIES: EGA
ACCESS DATA