Genomics

Dataset Information

0

EGAS00001001675-sc-20170705 - samples


ABSTRACT: A EGFR mutant NSCLC cell line which is sensitive to AZD9291 inhibition was mutagenised with the chemical mutagen ENU and then drug selected using a AZD9291. Single cell derived colonies were then manually picked and expanded in drug. Resistance was confirmed in a 14 day assay and DNA was collected. These then underwent targeted amplicon-based sequencing to confirm candidate resistance effectors hypothesised from currently available literature. This dataset contains all the data available for this study on 2017-07-05.

PROVIDER: EGAD00001003425 | EGA |

REPOSITORIES: EGA

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