Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Ena-DATASET-UH-tumor-30-04-2018-10:06:08:271-123 - samples

ABSTRACT: siRNA knockdown of 43 Allelic Imbalance target TFs followed by mRNA-seq done in triplicates in three (GP5D, LoVo, COLO320DM) different cell colorectal adenocarcinoma cell lines.

PROVIDER: EGAD00001004098 | EGA |

REPOSITORIES: EGA

ACCESS DATA

Json Xml

Similar Datasets

Dynamic allelic imbalance in early mouse embryo

Project description:Dynamic allelic imbalance in early mouse embryo

| PRJNA524173 | ENA

Allelic imbalance is a prevalent and tissue-specific feature of the mouse transcriptome

Project description:We perform a systematic classification of allelic imbalance in mouse hybrids derived from reciprocal crosses of divergent strains. We observe that deviation from balanced biallelic expression is common, occurring in ~20% of the mouse transcriptome. Allelic imbalance attributed to genotype is by far the most prevalent class and typically is tissue-specific. However, some genotype-based imbalance is maintained across tissues and is associated with greater genetic variation, especially in 5’ and 3’ termini of transcripts. We further identify novel random monoallelic and imprinted genes, and find that genotype can compete with parental origin even in the setting of large imprinted regions. PolyA-selected RNA-sequencing in F1 hybrid and parental cells of Mm. musculus and Mm. castaneus origin

2015-05-28 | E-GEOD-58524 | biostudies-arrayexpress

Dynamic allelic imbalance in early mouse embryo

Project description:We used a reciprocal crosses model to assess the allelic imbalance in early mouse embryo

2019-11-05 | GSE127106 | GEO

Allelic specificity of IGH-DUX4 translocation in acute lymphoblastic leukemia (ALL) [ATAC-seq]

Project description:In Nalm6, allelic imbalance was found at IGH-DUX4 translocation locus from ATAC-seq data.

2019-05-08 | GSE115482 | GEO

Allelic specificity of IGH-DUX4 translocation in acute lymphoblastic leukemia (ALL) [H3K27ac ChIP-seq]

Project description:In Nalm6, allelic imbalance was found at IGH-DUX4 translocation locus from H3K27ac ChIP-seq data.

2019-05-08 | GSE116137 | GEO

Cancer - immune cell interactions drive transitions to mesenchymal-like states in glioblastoma

Project description:To understand the diversity of expression states in model systems of Glioblastomas, we profiled 949 single cells from 13 mice at different timepoints by single-cell RNA sequencing, as well as 3483 cells from GBM celllines, 576 cells from OSM-treated vs control-treated mice, 2767 cells from OSM-treated vs control treated cell lines (MGG23, MGG75), 290 macrophage cells from mice OE OSM, and bulk RNA seq from triplicates after treatment with siRNA for 8 TFs known to regulate mesenchymal program.

2021-04-23 | GSE168004 | GEO

Allelic imbalance is a prevalent and tissue-specific feature of the mouse transcriptome

2015-05-28 | GSE58524 | GEO

OncoScan CNV SNP array data for MNG/PTC samples

Project description:Genome-wide copy number analysis using SNP-arrays (OncoScans) in multinodular goitres from individuals with the c.1552G>A;p.E518K mutation in DGCR8 show allelic imbalance at Chr22 in all samples. Likewise this event is confirmed in papillary thyroid tumors harboring the same alteration somatically. The only alteration common in all MNG and FvPTC samples was the allelic imbalance at the Chr22 in line with all samples showing an homozygous genotype at the DGCR8 locus

2019-11-01 | GSE135374 | GEO

Human colorectal cancer cell LC-MS/MS

Project description:Six non- and drug-resistant colorectal cancer cell lines were selected in this study, which were non-resistant cell lines: HCT116 and LoVo, four drug-resistant cell lines: HCT116-OxPt, HCT116-SN38, LoVo-OxPt, LoVo-SN38.Proteins extraced from three HCT116 related cell lines were labled and pooled together, and proteins from other three LoVo related cell lines were labled and pooled together.

2022-03-04 | PXD004070 | Pride

Effect of H19 Knockdown by siRNA on gene expression in C2C12 cells

Project description:We used microarrays to characterize the global changes in gene expression in C2C12 cells due to siRNA knockdown of long non-coding RNA H19 Control siRNA or siRNA specific for mouse H19 were transfected into day1 differentiating C2C12 myoblasts in triplicates. 40 H later total RNAs were isolated and subjected with microarray analysis.

2013-09-30 | E-GEOD-49535 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data