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58163526-63f7-452b-8f78-2c97eda05527 - samples

ABSTRACT: This dataset is composed of 86 samples: 15 samples of bronchoalveolar lavage fluid (BAL), 17 samples of non-malignant lung tissue, 14 samples of peritumoural tissue, 16 tumour tissues, 8 negative DNA extraction controls, 16 negative sampling controls for BAL. Samples were obtained from 17 NSCLC patients (average age 68 years). Sequenced region was 16S V3-V4. Fastq files are provided.

PROVIDER: EGAD00001006567 | EGA |

REPOSITORIES: EGA

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Characterisation of microbiota in saliva, bronchoalveolar lavage fluid, non-malignant, peritumoural and tumour tissue in non-small cell lung cancer patients: a cross-sectional clinical trial.

Bingula Rea R Filaire Edith E Molnar Ioana I Delmas Eve E Berthon Jean-Yves JY Vasson Marie-Paule MP Bernalier-Donadille Annick A Filaire Marc M

Respiratory research 20200525 1

<h4>Background</h4>While well-characterised on its molecular base, non-small cell lung cancer (NSCLC) and its interaction with local microbiota remains scarcely explored. Moreover, current studies vary in source of lung microbiota, from bronchoalveolar lavage fluid (BAL) to tissue, introducing potentially differing results. Therefore, the objective of this study was to provide detailed characterisation of the oral and multi-source lung microbiota of direct interest in lung cancer research. Since ...[more]

PMID: 32450847

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