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6c230511-9373-4a9b-bbba-dcbccba244dc - samples

ABSTRACT: In this study, we aimed to identify somatic structural variation of acute myeloid leukemia with complex karyotype (CK-AML) at the single-cell level and to investigate its direct consequence on the nucleosome occupancy using scNOVA approach. For this purpose, we performed strand-specific single-cell sequencing of primary leukemia samples from four CK-AML patients. We also performed strand-specific single-cell sequencing of two patient-derived xenografts (PDXs).

PROVIDER: EGAD00001011172 | EGA |

REPOSITORIES: EGA

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