Project description:Genome wide DNA methylation profiles of various human brain regions (cerebellum, occipital lobe, etc). The Illumina Infinium 450k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 480,000 CpGs. The dataset includes 130 samples. Multiple brain regions were assessed per subject. The goal was to evaluate the effect of HIV infection on DNA methylation levels. Genome wide DNA methylation profiles of various brain regions from HIV positive and negative subjects. The Illumina Infinium 450k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 480,000 CpGs. Dataset included 130 samples: 99 samples from HIV+ subjects and 31 samples from HIV- subjects.
Project description:Genome wide DNA methylation profiles of human pancreatic tissue. The Illumina Infinium 450k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 485,000 CpGs. Dataset includes in total 24 pancreatic tissue samples,12 samples of patients with ductal adenocarcinoma and 12 samples of healthy person. Bisulphite converted DNA from the 24 samples were hybridised to the Illumina Infinium 450k Human Methylation Beadchip.
Project description:Genome wide DNA methylation profiles of human muscle tissue. The Illumina Infinium 450k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 485,000 CpGs. Dataset includes 26 samples from Germany. The goal of the study was to evalute the relationship between body mass index and DNA methylation levels. Bisulphite converted DNA from the 26 samples were hybridised to the Illumina Infinium 450k Human Methylation Beadchip.
Project description:Genome wide DNA methylation profiles of human adipose tissue. The Illumina Infinium 450k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 485,000 CpGs. Dataset includes 32 samples from Germany. The goal of the study was to evalute the relationship between body mass index and DNA methylation levels. Bisulphite converted DNA from the 32 samples were hybridised to the Illumina Infinium 450k Human Methylation Beadchip.
Project description:Genome wide DNA methylation profiles of human Liver tissue. The Illumina Infinium 450k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 485,000 CpGs. Dataset includes 79 samples from Germany. The goal of the study was to evalute the relationship between body mass index and DNA methylation levels. Bisulphite converted DNA from the 79 samples were hybridised to the Illumina Infinium 450k Human Methylation Beadchip.
Project description:Genome wide DNA methylation profiles of human muscle tissue. The Illumina Infinium 450k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 485,000 CpGs. Dataset includes 26 samples from Germany. The goal of the study was to evalute the relationship between body mass index and DNA methylation levels.
Project description:Genome wide DNA methylation profiles of human Liver tissue. The Illumina Infinium 450k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 485,000 CpGs. Dataset includes 79 samples from Germany. The goal of the study was to evalute the relationship between body mass index and DNA methylation levels.
Project description:Genome wide DNA methylation profiles of human adipose tissue. The Illumina Infinium 450k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 485,000 CpGs. Dataset includes 32 samples from Germany. The goal of the study was to evalute the relationship between body mass index and DNA methylation levels.
Project description:Genome wide DNA methylation profiles of cerebellum from HIV positive and HIV negative human subjects. The Illumina Infinium 450k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 486,000 CpGs. Dataset included 20 subjects from the USA. The epigenetic clock software (Horvath 2013) was used to measure epigenetic age acceleration effects and to relate them to HIV status. Bisulphite converted DNA from the 20 samples were hybridised to the Illumina Infinium 450k Human Methylation Beadchip. 8 HIV+ subjects were compared to 12 HIV- subjects.
Project description:Genome wide DNA methylation profiles of Frontal Lobe from HIV positive and HIV negative human subjects. The Illumina Infinium 450k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 486,000 CpGs. Dataset included 33 subjects from the USA. The epigenetic clock software (Horvath 2013) was used to measure epigenetic age acceleration effects and to relate them to HIV status. Bisulphite converted DNA from the 33 samples were hybridised to the Illumina Infinium 450k Human Methylation Beadchip. 8 HIV+ subjects were compared to 25 HIV- subjects.