Dataset Information
Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children
Ontology highlight
ABSTRACT:
PROVIDER: EGAO00000000090 | EGA |
REPOSITORIES: EGA
Publications
Markers of survival and metastatic potential in childhood CNS primitive neuro-ectodermal brain tumours: an integrative genomic analysis.
The Lancet. Oncology 20120611 8
<h4>Background</h4>Childhood CNS primitive neuro-ectodermal brain tumours (PNETs) are very aggressive brain tumours for which the molecular features and best treatment approaches are unknown. We assessed a large cohort of these rare tumours to identify molecular markers to enhance clinical management of this disease.<h4>Methods</h4>We obtained 142 primary hemispheric CNS PNET samples from 20 institutions in nine countries and examined transcriptional profiles for a subset of 51 samples and copy ...[more]
