Dataset Information
German Cancer Research Center (DKFZ)
Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: PRJNA185822PRJNA241314PRJNA185821PRJNA185826PRJNA185825PRJNA185824PRJNA185823PRJNA185827
PROVIDER: EGAO00000000298 | EGA |
REPOSITORIES: EGA
Publications
Integrated clinical, whole-genome, and transcriptome analysis of multisampled lethal metastatic prostate cancer.
Cold Spring Harbor molecular case studies 20160501 3
We report the first combined analysis of whole-genome sequence, detailed clinical history, and transcriptome sequence of multiple prostate cancer metastases in a single patient (A21). Whole-genome and transcriptome sequence was obtained from nine anatomically separate metastases, and targeted DNA sequencing was performed in cancerous and noncancerous foci within the primary tumor specimen removed 5 yr before death. Transcriptome analysis revealed increased expression of androgen receptor (AR)-re ...[more]
