Other,Multiomics

Dataset Information

1K

DKFZ-HIPO

ABSTRACT: Organisation EGAO00000000713

PROVIDER: EGAO00000000713 | EGA |

REPOSITORIES: EGA

Json Xml
altmetric image

Publications

Mutational patterns and regulatory networks in epigenetic subgroups of meningioma.

Paramasivam Nagarajan N   Hübschmann Daniel D   Toprak Umut H UH   Ishaque Naveed N   Neidert Marian M   Schrimpf Daniel D   Stichel Damian D   Reuss David D   Sievers Philipp P   Reinhardt Annekathrin A   Wefers Annika K AK   Jones David T W DTW   Gu Zuguang Z   Werner Johannes J   Uhrig Sebastian S   Wirsching Hans-Georg HG   Schick Matthias M   Bewerunge-Hudler Melanie M   Beck Katja K   Brehmer Stephanie S   Urbschat Steffi S   Seiz-Rosenhagen Marcel M   Hänggi Daniel D   Herold-Mende Christel C   Ketter Ralf R   Eils Roland R   Ram Zvi Z   Pfister Stefan M SM   Wick Wolfgang W   Weller Michael M   Grossmann Rachel R   von Deimling Andreas A   Schlesner Matthias M   Sahm Felix F  

Acta neuropathologica 20190508 2

DNA methylation patterns delineate clinically relevant subgroups of meningioma. We previously established the six meningioma methylation classes (MC) benign 1-3, intermediate A and B, and malignant. Here, we set out to identify subgroup-specific mutational patterns and gene regulation. Whole genome sequencing was performed on 62 samples across all MCs and WHO grades from 62 patients with matched blood control, including 40 sporadic meningiomas and 22 meningiomas arising after radiation (Mrad). R  ...[more]

PMID: 31069492

Publication: 1/4

Similar Datasets

Other,Multiomics DKFZ
| EGAO00000000076 | EGA
Other,Multiomics DKFZ-IBIOS
| EGAO00000000036 | EGA
Other,Multiomics German Cancer Research Center (DKFZ)
| EGAO00000000298 | EGA
Other DKFZ-B080_DMG
| EGAO00000000661 | EGA
Other DKFZ-Epigenomics
| EGAO00000000385 | EGA
Other Deutsches Krebsforschungszentrum DKFZ
| EGAO00000001381 | EGA
Other DKFZ - German Cancer Research Centre
| EGAO00000001147 | EGA
Unknown Comparison of the IPSA and HIPO algorithms for interstitial tongue high-dose-rate brachytherapy.
| S-EPMC6171910 | biostudies-literature
Unknown Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
| S-EPMC6192650 | biostudies-literature
Unknown DNA methylation-based profiling of bone and soft tissue tumours: a validation study of the 'DKFZ Sarcoma Classifier'.
| S-EPMC8185366 | biostudies-literature