Dataset Information

Chinese Academy of Medical Science & Peking Union Medical College Hosipital (CAMS&PUMCH)

ABSTRACT: Organisation EGAO00000000927

PROVIDER: EGAO00000000927 | EGA |

REPOSITORIES: EGA

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Publications

Identification of prognostic biomarkers in hepatitis B virus-related hepatocellular carcinoma and stratification by integrative multi-omics analysis.

Miao Ruoyu R Luo Haitao H Zhou Huandi H Li Guangbing G Bu Dechao D Yang Xiaobo X Zhao Xue X Zhang Haohai H Liu Song S Zhong Ying Y Zou Zhen Z Zhao Yan Y Yu Kuntao K He Lian L Sang Xinting X Zhong Shouxian S Huang Jiefu J Wu Yan Y Miksad Rebecca A RA Robson Simon C SC Jiang Chengyu C Zhao Yi Y Zhao Haitao H

Journal of hepatology 20140522 4

<h4>Background & aims</h4>The differentiation of distinct multifocal hepatocellular carcinoma (HCC): multicentric disease vs. intrahepatic metastases, in which the management and prognosis varies substantively, remains problematic. We aim to stratify multifocal HCC and identify novel diagnostic and prognostic biomarkers by performing whole genome and transcriptome sequencing, as part of a multi-omics strategy.<h4>Methods</h4>A complete collection of tumour and somatic specimens (intrahepatic HCC ...[more]

PMID: 24859455

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Project description:China has a historic system of wide cycle tracks, many of which are now encroached by cars, buses and bus stops. Even with these conditions, college students still bicycle. On campuses, students park their bikes on facilities ranging from kick-stand-plazas to caged sheds with racks, pumps and an attendant. In other countries, including Canada, some of the newer cycle tracks need to be wider to accommodate an increasing number of bicyclists. Other countries will also need to improve their bike parking, which includes garage-basement cages and two-tiered racks. China could provide lessons about cycle tracks and bike parking. This study applied the Maslow Transportation Level of Service (LOS) theory, i.e., for cycle tracks and bike parking, only after the basic needs of safety and security are met for both vehicle occupants and bicyclists can the higher needs of convenience and comfort be met. With random clustering, a self-administered questionnaire was collected from 410 students in six dormitory buildings at Peking University in Beijing and an environmental scan of bicycle parking conducted in school/office and living areas. Cycle tracks (1 = very safe/5 = very unsafe) shared with moving cars were most unsafe (mean = 4.6), followed by sharing with parked cars (4.1) or bus stop users (4.1) (p < 0.001). Close to half thought campus bike parking lacked order. The most suggested parking facilities were sheds, security (guard or camera), bicycle racks and bicycle parking services (pumps, etc.). If parking were improved, three quarters indicated they would bicycle more. While caged sheds were preferred, in living areas with 1597 parked bikes, caged sheds were only 74.4% occupied. For the future of China's wide cycle tracks, perhaps a fence-separated bus lane beside a cycle track might be considered or, with China's recent increase in bike riding, shared bikes and E-bikes, perhaps cars/buses could be banned from the wide cycle tracks. In other countries, a widened cycle track entrance should deter cars. Everywhere, bike parking sheds could be built and redesigned with painted lines to offer more space and order, similar to car parking.

Dataset Information

Chinese Academy of Medical Science & Peking Union Medical College Hosipital (CAMS&PUMCH)

Publications

Identification of prognostic biomarkers in hepatitis B virus-related hepatocellular carcinoma and stratification by integrative multi-omics analysis.

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