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Dataset Information

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Department of Liver Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical


ABSTRACT: Organisation EGAO00000000933

PROVIDER: EGAO00000000933 | EGA |

REPOSITORIES: EGA

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Publications

Identification of prognostic biomarkers in hepatitis B virus-related hepatocellular carcinoma and stratification by integrative multi-omics analysis.

Miao Ruoyu R   Luo Haitao H   Zhou Huandi H   Li Guangbing G   Bu Dechao D   Yang Xiaobo X   Zhao Xue X   Zhang Haohai H   Liu Song S   Zhong Ying Y   Zou Zhen Z   Zhao Yan Y   Yu Kuntao K   He Lian L   Sang Xinting X   Zhong Shouxian S   Huang Jiefu J   Wu Yan Y   Miksad Rebecca A RA   Robson Simon C SC   Jiang Chengyu C   Zhao Yi Y   Zhao Haitao H  

Journal of hepatology 20140522 4


<h4>Background & aims</h4>The differentiation of distinct multifocal hepatocellular carcinoma (HCC): multicentric disease vs. intrahepatic metastases, in which the management and prognosis varies substantively, remains problematic. We aim to stratify multifocal HCC and identify novel diagnostic and prognostic biomarkers by performing whole genome and transcriptome sequencing, as part of a multi-omics strategy.<h4>Methods</h4>A complete collection of tumour and somatic specimens (intrahepatic HCC  ...[more]

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