Genomics

Dataset Information

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WTCCC case-control study for Breast cancer

ABSTRACT: WTCCC genome-wide case-control association study for Breast cancer (BC) using the 1958 British Birth Cohort collection as controls.

PROVIDER: EGAS00000000024 | EGA |

REPOSITORIES: EGA

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Publications

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.

Burton Paul R PR   Clayton David G DG   Cardon Lon R LR   Craddock Nick N   Deloukas Panos P   Duncanson Audrey A   Kwiatkowski Dominic P DP   McCarthy Mark I MI   Ouwehand Willem H WH   Samani Nilesh J NJ   Todd John A JA   Donnelly Peter P   Barrett Jeffrey C JC   Davison Dan D   Easton Doug D   Evans David M DM   Evans David M DM   Leung Hin-Tak HT   Marchini Jonathan L JL   Morris Andrew P AP   Spencer Chris C A CC   Tobin Martin D MD   Attwood Antony P AP   Boorman James P JP   Cant Barbara B   Everson Ursula U   Hussey Judith M JM   Jolley Jennifer D JD   Knight Alexandra S AS   Koch Kerstin K   Meech Elizabeth E   Nutland Sarah S   Prowse Christopher V CV   Stevens Helen E HE   Taylor Niall C NC   Walters Graham R GR   Walker Neil M NM   Watkins Nicholas A NA   Winzer Thilo T   Jones Richard W RW   McArdle Wendy L WL   Ring Susan M SM   Strachan David P DP   Pembrey Marcus M   Breen Gerome G   St Clair David D   Caesar Sian S   Gordon-Smith Katharine K   Jones Lisa L   Fraser Christine C   Green Elaine K EK   Grozeva Detelina D   Hamshere Marian L ML   Holmans Peter A PA   Jones Ian R IR   Kirov George G   Moskivina Valentina V   Nikolov Ivan I   O'Donovan Michael C MC   Owen Michael J MJ   Collier David A DA   Elkin Amanda A   Farmer Anne A   Williamson Richard R   McGuffin Peter P   Young Allan H AH   Ferrier I Nicol IN   Ball Stephen G SG   Balmforth Anthony J AJ   Barrett Jennifer H JH   Bishop Timothy D TD   Iles Mark M MM   Maqbool Azhar A   Yuldasheva Nadira N   Hall Alistair S AS   Braund Peter S PS   Dixon Richard J RJ   Mangino Massimo M   Stevens Suzanne S   Thompson John R JR   Bredin Francesca F   Tremelling Mark M   Parkes Miles M   Drummond Hazel H   Lees Charles W CW   Nimmo Elaine R ER   Satsangi Jack J   Fisher Sheila A SA   Forbes Alastair A   Lewis Cathryn M CM   Onnie Clive M CM   Prescott Natalie J NJ   Sanderson Jeremy J   Matthew Christopher G CG   Barbour Jamie J   Mohiuddin M Khalid MK   Todhunter Catherine E CE   Mansfield John C JC   Ahmad Tariq T   Cummings Fraser R FR   Jewell Derek P DP   Webster John J   Brown Morris J MJ   Lathrop Mark G MG   Connell John J   Dominiczak Anna A   Marcano Carolina A Braga CA   Burke Beverley B   Dobson Richard R   Gungadoo Johannie J   Lee Kate L KL   Munroe Patricia B PB   Newhouse Stephen J SJ   Onipinla Abiodun A   Wallace Chris C   Xue Mingzhan M   Caulfield Mark M   Farrall Martin M   Barton Anne A   Bruce Ian N IN   Donovan Hannah H   Eyre Steve S   Gilbert Paul D PD   Hilder Samantha L SL   Hinks Anne M AM   John Sally L SL   Potter Catherine C   Silman Alan J AJ   Symmons Deborah P M DP   Thomson Wendy W   Worthington Jane J   Dunger David B DB   Widmer Barry B   Frayling Timothy M TM   Freathy Rachel M RM   Lango Hana H   Perry John R B JR   Shields Beverley M BM   Weedon Michael N MN   Hattersley Andrew T AT   Hitman Graham A GA   Walker Mark M   Elliott Kate S KS   Groves Christopher J CJ   Lindgren Cecilia M CM   Rayner Nigel W NW   Timpson Nicolas J NJ   Zeggini Eleftheria E   Newport Melanie M   Sirugo Giorgio G   Lyons Emily E   Vannberg Fredrik F   Hill Adrian V S AV   Bradbury Linda A LA   Farrar Claire C   Pointon Jennifer J JJ   Wordsworth Paul P   Brown Matthew A MA   Franklyn Jayne A JA   Heward Joanne M JM   Simmonds Matthew J MJ   Gough Stephen C L SC   Seal Sheila S   Stratton Michael R MR   Rahman Nazneen N   Ban Maria M   Goris An A   Sawcer Stephen J SJ   Compston Alastair A   Conway David D   Jallow Muminatou M   Newport Melanie M   Sirugo Giorgio G   Rockett Kirk A KA   Bumpstead Suzannah J SJ   Chaney Amy A   Downes Kate K   Ghori Mohammed J R MJ   Gwilliam Rhian R   Hunt Sarah E SE   Inouye Michael M   Keniry Andrew A   King Emma E   McGinnis Ralph R   Potter Simon S   Ravindrarajah Rathi R   Whittaker Pamela P   Widden Claire C   Withers David D   Cardin Niall J NJ   Davison Dan D   Ferreira Teresa T   Pereira-Gale Joanne J   Hallgrimsdo'ttir Ingeleif B IB   Howie Bryan N BN   Su Zhan Z   Teo Yik Ying YY   Vukcevic Damjan D   Bentley David D   Brown Matthew A MA   Compston Alastair A   Farrall Martin M   Hall Alistair S AS   Hattersley Andrew T AT   Hill Adrian V S AV   Parkes Miles M   Pembrey Marcus M   Stratton Michael R MR   Mitchell Sarah L SL   Newby Paul R PR   Brand Oliver J OJ   Carr-Smith Jackie J   Pearce Simon H S SH   McGinnis R R   Keniry A A   Deloukas P P   Reveille John D JD   Zhou Xiaodong X   Sims Anne-Marie AM   Dowling Alison A   Taylor Jacqueline J   Doan Tracy T   Davis John C JC   Savage Laurie L   Ward Michael M MM   Learch Thomas L TL   Weisman Michael H MH   Brown Mathew M  

Nature genetics 20071021 11

We have genotyped 14,436 nonsynonymous SNPs (nsSNPs) and 897 major histocompatibility complex (MHC) tag SNPs from 1,000 independent cases of ankylosing spondylitis (AS), autoimmune thyroid disease (AITD), multiple sclerosis (MS) and breast cancer (BC). Comparing these data against a common control dataset derived from 1,500 randomly selected healthy British individuals, we report initial association and independent replication in a North American sample of two new loci related to ankylosing spon  ...[more]

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