Dataset Information
HLA has strongest association with IgA nephropathy in genome-wide analysis
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ABSTRACT:
PROVIDER: EGAS00000000031 | EGA |
REPOSITORIES: EGA
Publications
HLA has strongest association with IgA nephropathy in genome-wide analysis.
Journal of the American Society of Nephrology : JASN 20100701 10
Demographic and family studies support the existence of a genetic contribution to the pathogenesis of IgA nephropathy, but results from genetic association studies of candidate genes are inconsistent. To systematically survey common genetic variation in this disease, we performed a genome-wide analysis in a cohort of patients with IgA nephropathy selected from the UK Glomerulonephritis DNA Bank. We used two groups of controls: parents of affected individuals and previously genotyped, unaffected, ...[more]
