Genetic and Functional Drivers of Diffuse Large B Cell Lymphoma
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PROVIDER: EGAS00001002606 | EGA |
REPOSITORIES: EGA
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Genetic and Functional Drivers of Diffuse Large B Cell Lymphoma.
Reddy Anupama A Zhang Jenny J Davis Nicholas S NS Moffitt Andrea B AB Love Cassandra L CL Waldrop Alexander A Leppa Sirpa S Pasanen Annika A Meriranta Leo L Karjalainen-Lindsberg Marja-Liisa ML Nørgaard Peter P Pedersen Mette M Gang Anne O AO Høgdall Estrid E Heavican Tayla B TB Lone Waseem W Iqbal Javeed J Qin Qiu Q Li Guojie G Kim So Young SY Healy Jane J Richards Kristy L KL Fedoriw Yuri Y Bernal-Mizrachi Leon L Koff Jean L JL Staton Ashley D AD Flowers Christopher R CR Paltiel Ora O Goldschmidt Neta N Calaminici Maria M Clear Andrew A Gribben John J Nguyen Evelyn E Czader Magdalena B MB Ondrejka Sarah L SL Collie Angela A Hsi Eric D ED Tse Eric E Au-Yeung Rex K H RKH Kwong Yok-Lam YL Srivastava Gopesh G Choi William W L WWL Evens Andrew M AM Pilichowska Monika M Sengar Manju M Reddy Nishitha N Li Shaoying S Chadburn Amy A Gordon Leo I LI Jaffe Elaine S ES Levy Shawn S Rempel Rachel R Tzeng Tiffany T Happ Lanie E LE Dave Tushar T Rajagopalan Deepthi D Datta Jyotishka J Dunson David B DB Dave Sandeep S SS
Cell 20171001 2
Diffuse large B cell lymphoma (DLBCL) is the most common form of blood cancer and is characterized by a striking degree of genetic and clinical heterogeneity. This heterogeneity poses a major barrier to understanding the genetic basis of the disease and its response to therapy. Here, we performed an integrative analysis of whole-exome sequencing and transcriptome sequencing in a cohort of 1,001 DLBCL patients to comprehensively define the landscape of 150 genetic drivers of the disease. We chara ...[more]
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| phs000364 | dbGaP
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