Genomics

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WGS and WES of pediatric osteosarcoma


ABSTRACT: Despite being the most common childhood bone tumor, the genomic characterization of osteosarcoma remains incomplete. Very few metastatic cases have been sequenced to date, a required step to better understand the progression and evolution of this tumor. Here, we present an integrative analysis of whole genome and whole exome sequencing (WGS and WES) of a cohort of primary and metastatic pediatric osteosarcoma, in order to identify recurrent genomic alterations between and within patients.

PROVIDER: EGAS00001003342 | EGA |

REPOSITORIES: EGA

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