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Exome and Whole-Genome Sequencing of Central African Hunter-Gatherers and Agriculturalists

ABSTRACT: To investigate how human populations have adapted to the equatorial rainforest, we generated 266 high-coverage exomes, analyzed in combination with 300 published exomes, from 14 populations of African rainforest hunter-gatherers and farmers, together with 40 newly-generated, low-coverage genomes. Genome scans for positive selection and signatures of polygenic selection provide evidence for local adaptation of hunter-gatherers to the African rainforest.

PROVIDER: EGAS00001003722 | EGA |

REPOSITORIES: EGA

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