Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Signals of positive selection in Peruvians from three ecological regions

ABSTRACT: In this study, genome-wide single-nucleotide polymorphism (SNP) data (Illumina InfiniumÃ‚Â® MEGA array) was gathered for 200 individuals distributed across PerÃƒÂº, and then analyzed to investigate signals of recent positive selection specific to populations living in the high-altitude environments of the Andes, the arid Pacific coast and the Amazon rainforest.

PROVIDER: EGAS00001005692 | EGA |

REPOSITORIES: EGA

ACCESS DATA

Json Xml

Similar Datasets

Moderate hypoxia influence at intermediate altitude in Argentinean Andes

Project description:This study evaluates genetic and phenotypic variation in the intermediate altitude Calchaquí population living in the Calchaquí Valleys of the Argentinean Andes in the town of Cachi at 2300 m. This study attempts to pinpoint evolutionary mechanisms underlying adaptation to moderate hypoxia at a intermediate altitude.

2014-04-05 | GSE56518 | GEO

Moderate hypoxia influence at intermediate altitude in Argentinean Andes

Project description:This study evaluates genetic and phenotypic variation in the intermediate altitude CalchaquÃ population living in the CalchaquÃ Valleys of the Argentinean Andes in the town of Cachi at 2300 m. This study attempts to pinpoint evolutionary mechanisms underlying adaptation to moderate hypoxia at a intermediate altitude. DNA from 24 saliva samples of CalchaquÃes living at 2300 m in Cachi in the Province of Salta in Argentina was genotyped.

2014-04-05 | E-GEOD-56518 | biostudies-arrayexpress

Population Genomics of Native Americans from Andes and Amazon

Project description:Using genome-wide information of Native Americans from Andes and Amazon we addressed questions about : the Andes-Amazon dichotomy, the Andean homogenization and how cultural and socioeconomic interactions revealed by archaeology were accompanied by gene flow, specifically in northern Peru. Moreover, this demographic history allowed for cases of positive natural selection in the high and arid Andes vs. the low Amazon tropical forest

| EGAS00001004639 | EGA

Transcriptomes of tissues of the razor clam Sinonovacula constricta

Project description:The razor clam Sinonovacula constricta (Lamarck 1818) is a famous marine bivalve species that widely distributed along the western Pacific coast with important economical and nutritional values. During the evolution, S. constricta has formed specific biological features to adapt to its living habit. To clarify the underlying molecular mechanism in forming the specific biological features, the tissues of siphon, gill, labial palp, foot, mantle, and intestine of S. constricta were subjected to RNA-sequencing. The results showed significant differences existed in gene expression among different tissues, which provided a molecular framework for understanding the differentiation of S. constricta tissues and their underlying specific biological functions.

2023-07-02 | GSE235883 | GEO

dataset_raw_NativesAmericans_LDGH_august2020

Project description:Genome-wide data for 98 Native American individuals from Andes and Amazon

| EGAD00010001958 | EGA

Argentinean high altitude adaptation

Project description:This study evaluates genetic and phenotypic variation in the high altitude Colla population living in the Argentinean Andes above 3500 m. They were compared to the Wichí population living in the nearby lowlands of the Gran Chaco region. This study attempts to pinpoint evolutionary mechanisms underlying adaptation to hypobaric hypoxia. We have genotyped 25 individuals from both populations for 730,525 SNPs.

2014-02-20 | GSE55175 | GEO

Argentinean high altitude adaptation

Project description:This study evaluates genetic and phenotypic variation in the high altitude Colla population living in the Argentinean Andes above 3500 m. They were compared to the WichÃ population living in the nearby lowlands of the Gran Chaco region. This study attempts to pinpoint evolutionary mechanisms underlying adaptation to hypobaric hypoxia. We have genotyped 25 individuals from both populations for 730,525 SNPs. DNA from 25 saliva samples from Collas living >3500 m and 25 saliva samples from WichÃ living <500 m from the Province of Salta in Argentina was genotyped

2014-02-20 | E-GEOD-55175 | biostudies-arrayexpress

Project description:Horse flies of the Amazon Rainforest

| PRJNA387036 | ENA

Genome wide information of Peruvian Native American

Project description:Peruvian Native American individuals were genotyped as part of the Peruvian Genome Project (PGP). This data was used to infer population structure, demographic history and natural selection. We addressed question about gene flow across the Andes and Natural Selection in Andes and Amazon

| EGAS00001004650 | EGA

Natural selection has contributed to functional immune response differences between human hunter-gatherers and agriculturalists

Project description:The shift from a hunter-gatherer (HG) to an agricultural (AG) mode of subsistence is believed to have been associated with profound changes in the burden and diversity of pathogens across human populations. Yet, the extent to which the advent of agriculture impacted the evolution of the human immune system remains unknown. Here we present a comparative study of variation in the transcriptional responses of peripheral blood mononuclear cells (PBMCs) to bacterial and viral stimuli between the Batwa, a rainforest hunter-gatherer, and the Bakiga, an agriculturalist population from Central Africa. We observed increased divergence between hunter-gatherers and farmers in the transcriptional response to viruses compared to that for bacterial stimuli. We demonstrate that a significant fraction of these transcriptional differences are under genetic control, and we show that positive natural selection has helped to shape population differences in immune regulation. Unexpectedly, we found stronger signatures of recent natural selection in the rainforest hunter-gatherers, which argues against the popularized notion that shifts in pathogen exposure due to the advent of agriculture imposed radically heightened selective pressures in agriculturalist populations.

2018-09-27 | GSE120502 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data