Genomics

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Isoform-level profiling of m6A modifications in human brain


ABSTRACT: Oxford Nanopore direct RNA sequencing (DRS) can quantify isoform expression, modifications and polyA tail lengths, enabling simultaneous investigation of the transcriptome and epitranscriptome. We applied DRS to three post-mortem human brain regions: prefrontal cortex, caudate nucleus and cerebellum.

PROVIDER: EGAS00001007742 | EGA |

REPOSITORIES: EGA

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