Genomics

Dataset Information

0

Noninvasive prenatal testing of alpha-thalassemia and beta-thalassemia through population-based parental haplotyping


ABSTRACT: Noninvasive prenatal testing (NIPT) of recessive monogenic diseases heavily depends on the correct parental haplotypes. However, family-based genetic haplotyping (FBH) requires pedigrees, and molecular haplotyping remains a major challenge due to its high cost, long processing time, and complex procedure. Here, we propose a new approach termed population-based haplotyping NIPT (PBH-NIPT) using thalassemia as a prototype.

INSTRUMENT(S): BGISEQ-500

ORGANISM(S): Homo Sapiens

SUBMITTER: Tianjin Medical Laboratory, BGI-Tianjin 

PROVIDER: PRJEB42529 | EVA | 2021-01-18

REPOSITORIES: EVA

Similar Datasets

2013-11-03 | E-GEOD-48592 | biostudies-arrayexpress
2020-02-11 | GSE136702 | GEO
2020-02-11 | GSE136693 | GEO
2020-02-11 | GSE136686 | GEO
2013-11-03 | GSE48592 | GEO
2012-10-01 | GSE17318 | GEO
2021-08-18 | GSE178156 | GEO
2020-08-31 | GSE136270 | GEO
2017-11-01 | GSE94918 | GEO
| PRJNA573682 | ENA