Genomics

Dataset Information

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Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos


ABSTRACT: Single cell deep mtDNA sequencing of in vivo human female PGCs showed rare variants reaching higher heteroplasmy levels in late PGCs, consistent with the observed genetic bottleneck.

INSTRUMENT(S): Illumina MiSeq

ORGANISM(S): Homo Sapiens

SUBMITTER: University of Cambridge 

PROVIDER: PRJEB56092 | EVA | 2022-09-18

REPOSITORIES: EVA

Dataset's files

Source:
Action DRS
Single_cell_deep_sequencing_merged.vcf.csi Other
Single_cell_deep_sequencing_merged.vcf.gz Vcf
Single_cell_deep_sequencing_merged.vcf.gz.csi Vcf
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