Transcriptomics

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Transcriptome-wide analysis of roles for tRNA modifications in translational regulation


ABSTRACT: Covalent nucleotide modifications in noncoding RNAs such as tRNAs affect a plethora of biological processes, with new functions continuing to be discovered for even well-known tRNA modifications. To systematically compare the functions of a large set of ncRNA modifications in gene regulation, we carried out ribosome profiling and RNA-Seq in budding yeast for 57 nonessential genes involved in tRNA modification.

ORGANISM(S): Saccharomyces cerevisiae

PROVIDER: GSE100626 | GEO | 2017/06/29

SECONDARY ACCESSION(S): PRJNA392312

REPOSITORIES: GEO

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