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Transcriptome sequencing of human coronary artery smooth muscle cell under treatment of nitrated fatty acid

ABSTRACT: RNA-seq profiling of human coronary artery smooth muscle cells under treatment of nitrated conjugated linoleic acids (NO2-CLA)

ORGANISM(S): Homo sapiens

PROVIDER: GSE100676 | GEO | 2018/05/31

REPOSITORIES: GEO

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Transcriptome of human coronory endothelial cells in response to nitro-conjugated linoleic acid

Project description:In the present study, a distinct transcriptome regulated by NO2-CLA was revealed in primary human coronary artery endothelial cells (HCAECs) through RNA sequencing. Differential gene expression and pathway enrichment analysis identified numerous regulatory networks of cell cycle regulation, inflammation and redox responses, nitric oxide biosynthesis, hypoxia and chaperones in response to NO2-CLA, suggesting potent and diverse effects of NO2-CLA on cellular processes.

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Gene expression in adipose, liver and skeletal muscle of mice fed a diet with c9, t11 conjugated linoleic acid enriched beef

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Transcription profiling of mouse adipocytes treated with trans-10, cis-12 conjugated linoleic acid activates the integrated stress response pathway in adipocytes (GEO Super Series)

Project description:This SuperSeries is composed of the following subset Series:; GSE8679: Gene expression in mouse white adipose tissue; GSE8681: Gene expression in mouse 3T3-L1 adipocyte tissue culture treated with CLA; GSE8682: Gene expression in mouse 3T3-L1 adipocyte tissue culture treated with tunicamycin; GSE8683: Gene expression in 3T3-L1 mouse tissue (preadipocytes) treated with Trans-10,Cis-12 conjugated linoleic acid(t10c12 CLA); GSE8684: Gene expression in mouse 3T3-L1 adipocyte tissue culture treated with cis-9,trans-11 conjugated linoleic acid(c9t11 CLA) Experiment Overall Design: Refer to individual Series

2008-06-20 | E-GEOD-11384 | biostudies-arrayexpress

gene expression in human subcutaneous adipose tissue after CLA intervention

Project description:Iisomer-specific effects of conjugated linoleic (CLA) supplementation on gene expression with particular consideration of the PPAR 2 Pro12Ala SNP in human adipose tissue.

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Transcription profiling of mouse white adipose tissue from mice fed trans-10, cis-12 conjugated linoleic acid to determine the processes involved in the generated inflammation and de-lipidation of the adipose tissue

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Gene expression in adipose, liver and skeletal muscle of mice fed a diet with c9, t11 conjugated linoleic acid enriched beef

Project description:Conjugated Linoleic Acid (CLA) is a collective term for the positional and geometric isomers of linoleic acid. In recent years CLA has been reported to have anti-carcinogenic, anti-obesity, anti-inflammatory and anti-artherogenic effects. The aim of this study was to determine the effects of a natural high-CLA enriched beef source on three primary insulin responsive tissues: adipose, liver and skeletal muscle. ob/ob mice were assigned to one of two diets: a control beef diet, low in c9, t11-CLA (control diet) or a c9, t11-CLA enriched beef diet. After a 28 day feeding trial, RNA was extracted from adipose, liver and skeletal muscle tissue and hybridized to Affymetrix microarrays.

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Homo sapiens

Project description:Conjugated linoleic acid (CLA) and Caco-2 cells

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Gene expression in mouse 3T3-L1 adipocyte tissue culture treated with cis-9,trans-11 conjugated linoleic acid(c9t11 CLA)

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2008-01-11 | GSE8681 | GEO

Gene expression in mouse white adipose tissue

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