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CD95L derived si- and shRNAs kill cancer cells through an RNAi mechanism by targeting survival genes [shL1.RNAseq.lg]

ABSTRACT: We provide evidence that shRNAs and siRNAs derived from CD95 and CD95L preferentially target the 3' UTRs of survival genes culminating in a very robust mode of cell death we call DISE (Death Induced by Survival gene Elimination)

ORGANISM(S): Homo sapiens

PROVIDER: GSE101157 | GEO | 2017/09/16

SECONDARY ACCESSION(S): PRJNA393824

REPOSITORIES: GEO

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