Transcriptomics

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Gene expression profiles of mouse embryonic fibroblasts (MEFs), induced cardiomyocytes (iCMs) and heart.


ABSTRACT: Global gene expression patterns of the iCMs shift from a MEF state toward a cardiac-like phenotype by Gata4/Mef2c/Tbx5 (GMT) or GMT/Hand2 (GHMT) transduction at 2 and 4 weeks after transduction (2W, 4W). Hand2 upregulated a panel of cardiac genes and suppressed cell cylce genes during cardiac reprogramming.

ORGANISM(S): Mus musculus

PROVIDER: GSE101578 | GEO | 2017/09/26

SECONDARY ACCESSION(S): PRJNA394871

REPOSITORIES: GEO

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