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Oncogenes hijack the stress response machinery in T cell acute lymphoblastic leukemia [GRO-Seq]

ABSTRACT: Oncogenes NOTCH1 and MYC directly regulate HSF1 and other critical proteins of the stress-response pathway in T-ALL. This GRO-Seq experiment demonstrates that release from NOTCH1 inhibition results in upregulation of HSF1 and other key HSPs.

ORGANISM(S): Homo sapiens

PROVIDER: GSE101803 | GEO | 2018/03/20

REPOSITORIES: GEO

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Hijacking of stress response machinery by oncogenes in acute leukaemia [RNA-seq]

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