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Genome-wide maps of RNA polymerase II occupancy in immortalized MEF cells [ChIP-seq]

ABSTRACT: We report the application of ChIP-seq using an anti-RNA pol II antibody to determine changes in RNAP II occupancy patterns genome-wide. We found that as a result of MYC expression, RNAP II levels increased at both the promoter and gene body regions. This suggests that MYC increases the amount of both the initiation and elongation steps of trasncription globally.

ORGANISM(S): Mus musculus

PROVIDER: GSE102916 | GEO | 2018/08/20

REPOSITORIES: GEO

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Genome-wide maps of RNA polymerase II occupancy and transcriptome profile in response to expression of ectopic MYC proteins in immortalized MEF cells

Project description:Genome-wide maps of RNA polymerase II occupancy and transcriptome profile in response to expression of ectopic MYC proteins in immortalized MEF cells

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Genome-wide maps of RNA polymerase II occupancy and transcriptome profile in response to expression of ectopic MYC proteins in immortalized MEF cells

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