Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Identifying SC1-regulated miRNAs in the J1 mESCs

ABSTRACT: It has been demonstrated that SC1 (Pluripotin) promotes self-renewal of mouse embryonic stem cells. To better understand miRNAs regulated by SC1 directly or indirectly in mouse embryonic stem cells, we performed next generation sequencing (NGS) to identify small RNAs with expression changes after SC1 treatment.

ORGANISM(S): Mus musculus

PROVIDER: GSE103015 | GEO | 2017/10/23

SECONDARY ACCESSION(S): PRJNA399757

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Identifying SC1-regulated mRNA and lncRNA in the J1 mESCs

Project description:It has been demonstrated that SC1 (Pluripotin) promotes self-renewal of mouse embryonic stem cells, however, the target genes of SC1 are not fully understood. To better understand the downstream target genes of SC1, we performed Microarray analysis to identify their downstream targets. The data show the genes regulated by SC1.

2018-08-01 | GSE102879 | GEO

Identifying PD0325901-regulated genes in the J1 mESCs

Project description:It has been demonstrated that PD0325901 promotes self-renewal of mouse embryonic stem cells, however, the target genes of PD0325901 are not fully understood. To better understand the downstream target genes of PD0325901, we performed Microarray analyses to identify their downstream targets. The data show the genes regulated by PD0325901.

2016-05-17 | GSE67534 | GEO

Identifying CHIR99021 and AICAR-regulated genes in the J1 mESCs

Project description:It has been demonstrated that CHIR99021 promotes self-renewal of mouse embryonic stem cells, however, the target genes of CHIR99021 is not fully understood. AICAR is the activator of AMP-activated protein kinase. It is reported that AICAR plays important role in mouse embryonic stem cells, however the moleculor mechanism of this phenomenon is unknown. To better understand the downstream target genes of CHIR99021 and AICAR, we performed Microarray analyses to identify their downstream targets. The data show the genes regulated by CHIR99021 or AICAR.

2013-01-01 | GSE40959 | GEO

Identifying PD0325901-regulated genes in the J1 mESCs

2016-05-17 | E-GEOD-67534 | biostudies-arrayexpress

Identifying CHIR99021 and AICAR-regulated genes in the J1 mESCs

2013-01-01 | E-GEOD-40959 | biostudies-arrayexpress

Identifying vitamin C and RA-regulated genes in the J1 mESCs

Project description:It has been demonstrated that vitamin C enhances reprogramming efficiency during inducing pluripotent stem cells, however, the underlying mechanisms are not fully understood. To find the downstream target genes of vitamin C and investigate the mechanism of vitamin C on reprogramming promotion, we performed Microarray analyses to identify its downstream targets. Retinoic acid (RA), a stimulus molecule for cellular differentiation, is set as negative control. The data show the genes regulated by vitamin C or RA.

2014-01-21 | GSE43405 | GEO

Identifying vitamin C and RA-regulated genes in the J1 mESCs

2014-01-21 | E-GEOD-43405 | biostudies-arrayexpress

Deep sequencing identifies PD0325901 modulated microRNAs in the J1 mESCs

Project description:PD0325901 is involved in improving reprogramming efficiency during inducing pluripotent stem cells (iPSC) or maintain a blastocyst-like state in embryonic stem cells (ESC). However, the knowledge about this small molecule regulating miRNAs in ESC was limited. To understand the role of miRNAs during PD03-induced ESC maintenance and gain an insight how PD0325901 regulates miRNAs expression; we performed small RNA sequencing using Illumina HiSeq 2000 under the compounds treatment. The data show the miRNAs regulated by PD0325901.

2016-05-17 | GSE67570 | GEO

RBPs proteome in HEK293 cells, mESCs and mouse organs

Project description:Identification of RBPs proteome in HEK293 cells, mouse embryonic stem cells (mESCs) and adult mouse primary organs (brain, heart, lung, kidney, liver)

2024-08-26 | PXD037105 | Pride