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Gene expression patterns define the hepatocyte-like cells derived by different strategies [ChIP-seq]

ABSTRACT: We analyzed the active H3K27 acetylation (H3K27ac) histone marker in hiPSC-Heps and hiHeps.The genome-wide H3K27ac occupancy analysis exhibited different patterns among these 4 types of cells. In accordance with the RNA-seq clustering results, the H3K27ac modifications of genes in seven clusters matched well with the active gene expressions in different cell types.

ORGANISM(S): Homo sapiens

PROVIDER: GSE103077 | GEO | 2017/11/23

SECONDARY ACCESSION(S): PRJNA400276

REPOSITORIES: GEO

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