Transcriptomics

Dataset Information

0

CARM1/PRMT4 is essential for myeloid leukemogenesis but dispensable for normal hematopoiesis


ABSTRACT: We investigated the role of PRMT4 in normal and malignant hematopoiesis. We found that knockdown of PRMT4 impairs cell cycle progression, induces apoptosis, and downgretulateds E2F target genes in leukemia cell lines, identifying several mechanisms for the leukemia-specific dependence on PRMT4.

ORGANISM(S): Homo sapiens

PROVIDER: GSE103528 | GEO | 2018/06/10

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

| S-EPMC6191185 | biostudies-literature
2017-09-30 | GSE104138 | GEO
| S-EPMC5755044 | biostudies-literature
2010-07-21 | E-GEOD-22778 | biostudies-arrayexpress
| PRJNA411792 | ENA
2013-12-19 | E-GEOD-46056 | biostudies-arrayexpress
| S-EPMC4120120 | biostudies-literature
2013-12-19 | GSE46056 | GEO
| S-EPMC2974602 | biostudies-literature
2014-04-03 | E-GEOD-56456 | biostudies-arrayexpress