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Angiogenic factor imbalance precedes complement deposition in the placenta of preeclamptic-like BPH/5 mice

ABSTRACT: BPH/5 mice are an inbred strain with “borderline hypertension” that spontaneously develops both maternal and fetal hallmarks of preeclampsia. RNA-Seq analysis of BPH/5 uterine implantation sites at embryonic day 7.5, the peak of decidualization, identifies differential expression of inflammatory response genes, including members of the complement family, compared to C57 controls.

ORGANISM(S): Mus musculus

PROVIDER: GSE103670 | GEO | 2018/01/04

SECONDARY ACCESSION(S): PRJNA404000

REPOSITORIES: GEO

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Angiogenic factor imbalance precedes complement deposition in placentae of the BPH/5 model of preeclampsia.

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