Transcriptomics

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Molecular characterization of chick anterior and posterior half-scleorotomes by RNA-sequencing.


ABSTRACT: During amniote peripheral nervous system development, segmentation ensures the correct patterning of the spinal nerves relative to vertebral column. Along the antero-posterior (rostro-caudal) axis, each somite-derived half-sclerotome has intrinsic molecular properties that govern this segmentation process. Posterior half-sclerotomes express repellent molecules to restrict axon growth and neural crest migration to anterior half-sclerotomes. Here, we report an RNA-sequencing-based molecular characterization of anterior and posterior half-sclerotomes, using the chick embryo as a model organism.

ORGANISM(S): Gallus gallus

PROVIDER: GSE103748 | GEO | 2020/09/12

REPOSITORIES: GEO

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