Transcriptomics

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A to I editing of the 3'-UTR landscape regulates gene translation during retinal development


ABSTRACT: We used parallel ribosome profiling and RNA sequencing to investigate the relationship between RNA editing and translation. Through systematically profiling mouse tissues from different developmental stages, we found dynamic changes in A-to-I RNA editome during retinal development. Further analysis revealed that altered translational efficiency in retinal development correlates with dynamics of A-to-I RNA editome.

ORGANISM(S): Mus musculus

PROVIDER: GSE104884 | GEO | 2023/10/01

REPOSITORIES: GEO

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