Transcriptomics

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RNA-sequencing of in vitro differentiated WT and Chi3l1 KO Th1 cell


ABSTRACT: We report the differential mRNA expressino of WT and Chi3l1 KO Th1 cells. We cultured WT and Chi3l1 KO naive CD4 T cells under Th1 skewing condition : plate-bound anti-CD3/28 antibody (2ug/mL), IL-12 0.2ng/mL, IL-2 50U/mL, anti-IL-4 neutralizing antibody 2ug/mL, for 3 days. We found different Th1 regulatory and tumoricidal-related gene expression in Chi3l1 KO T cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE105056 | GEO | 2018/02/13

REPOSITORIES: GEO

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