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RNA-sequencing of in vitro differentiated WT and Chi3l1 KO Th1 cell

ABSTRACT: RNA-sequencing of in vitro differentiated WT and Chi3l1 KO Th1 cell

PROVIDER: PRJNA414488 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR6179205_1.fastq.gz	Fastqsanger.gz
	SRR6179205_2.fastq.gz	Fastqsanger.gz
	SRR6179206_1.fastq.gz	Fastqsanger.gz
	SRR6179206_2.fastq.gz	Fastqsanger.gz

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RNA-sequencing of in vitro differentiated WT and Chi3l1 KO Th1 cell

Project description:We report the differential mRNA expressino of WT and Chi3l1 KO Th1 cells. We cultured WT and Chi3l1 KO naive CD4 T cells under Th1 skewing condition : plate-bound anti-CD3/28 antibody (2ug/mL), IL-12 0.2ng/mL, IL-2 50U/mL, anti-IL-4 neutralizing antibody 2ug/mL, for 3 days. We found different Th1 regulatory and tumoricidal-related gene expression in Chi3l1 KO T cells.

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