Transcriptomics

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Expression data from endothelial cells induced from bone marrow mesenchymal stem cells with SCD1 overexpression


ABSTRACT: Bone marrow mesenchymal stem cells (BM-MSCs) are of multi-differentiating potential and has been demonstrated to have the ability to differentiate into endothelial cells. Stearoyl-CoA desaturase 1 (SCD1) is a key enzyme in lipid metabolism, which can convert saturated fatty acids into unsaturated fatty acids. We used lentivirus to transfected SCD1 gene into BM-MSCs and found that overexpression of SCD1 could promote the differentiation of BM-MSCs into endothelial cells. We used microarrays to detect the differential gene expression profile of endothelial induced BM-MSCs with SCD1 overexpression.

ORGANISM(S): Homo sapiens

PROVIDER: GSE106596 | GEO | 2017/11/07

SECONDARY ACCESSION(S): PRJNA417317

REPOSITORIES: GEO

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