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Gene expression in MLE-12 cells transfected with microRNA (miRNA; miR) mimics upon influenza virus infection

ABSTRACT: To clarify the gene expression profile in MLE-12 cells transfected with microRNA mimics upon influenza virus infection, we transfected microRNA mimics (mmu-miR-483-3p or Negative control miRNA) into MLE-12 cells and infected A/Puerto Rico/8/1934 (PR8) strain at an MOI of 2 at 24 hours post transfection. RNA was isolated from cells at 12 hours post infection. We found that miR-483-3p transfection down-regulated the genes involved in the innate immunity regulation upon influenza virus infection.

ORGANISM(S): Mus musculus

PROVIDER: GSE107108 | GEO | 2018/06/08

REPOSITORIES: GEO

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