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Expression data from TCF19 knockdown in HepG2 cells maintained under high glucose (40mM) condition

ABSTRACT: Changes in concentration of glucose in the cellular environment results in a variety of changes in the transcription program. Liver is the primary organ for metabolic regulation in the body, and hence, any surge in circulating blood glucose leads to changes in transcriptional states of important enzymes tasked to maintain metabolic homeostasis. Chromatin modification reader proteins play an important role in maintaining metabolic homeostasis by identification of the histone modification, and facilitating recruitment of chromatin remodelling enzymes. We knocked down an important reader domain containing protein, TCF19, in human hepatocellular carcinoma cells ( HepG2) maintained under high glucose condition and used microarray to investigate the changes in gene expression profile.

ORGANISM(S): Homo sapiens

PROVIDER: GSE107471 | GEO | 2018/02/13

REPOSITORIES: GEO

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