Transcriptomics

Dataset Information

0

Recombinant Surfactant Protein D reverses expression of specific genes induced by HIV-1 in EpiVaginal Tissues: Clues for a protective response


ABSTRACT: We report the HIV-1 induced gene signature of vaginal tissues (EpiVaginalTM, MatTek Corporation, Ashland, MA) using a customised ex vivo model that mimics the vaginal transmission of HIV-1. Importantly, we demonstrate that recombinant fragment of human Surfactant Protein D (rhSP-D) (Mahajan et al., 2008) treated EpiVaginal tissues exhibited a remarkable but selective reversal of HIV-1 specific gene signature suggesting that epithelial behaviour significantly influences transmission events.

ORGANISM(S): Homo sapiens

PROVIDER: GSE107478 | GEO | 2018/11/29

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2023-08-01 | GSE182066 | GEO
2014-10-16 | GSE62395 | GEO
2020-06-07 | GSE99800 | GEO
2014-10-16 | GSE62397 | GEO
2014-03-01 | E-GEOD-44914 | biostudies-arrayexpress
2014-03-01 | GSE44914 | GEO
2013-02-01 | E-GEOD-42291 | biostudies-arrayexpress
2013-02-01 | GSE42291 | GEO
2014-01-29 | E-GEOD-49892 | biostudies-arrayexpress
2014-01-29 | GSE49892 | GEO