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DNA methylation maps of mouse NSCs treated with naloxone

ABSTRACT: In our study,we examined the effects of naloxone (an opioid receptor antagonist) on NSCs (neural stem cells) proliferation and differenntiation. Briefly, we treated NSCs with naloxone in the proliferation and differentiation system. Naloxone was shown to acclerate NSCs proliferation and increase neural differentiation.To investigate how DNA methylation is affected upon naloxone treatment, cells cultured 3 days with naloxone and cells differentiated with naloxone at D2 were collected, genomic DNA was extracted and subjected to RRBS analysis.

ORGANISM(S): Mus musculus

PROVIDER: GSE107525 | GEO | 2020/03/04

REPOSITORIES: GEO

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