Intestinal DNA methylome of preterm pigs
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ABSTRACT: DNA methylation plays important roles in normal development as well as sensing environmental exposures, thereby regulating transcription that is associated with cellular functions. Shortened gestational age and unexpected exposure to milk and microbes at the wrong time may affect intestinal development and health via DNA methylation. The present studies aimed to characterize the intestinal DNA methylomes of preterm neonates at birth and during postnatal development, in order to understand the cellular basis of the immature intestine and its interaction with early nutrition.
ORGANISM(S): Sus scrofa
PROVIDER: GSE108284 | GEO | 2018/12/18
REPOSITORIES: GEO
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