RNA deep sequencing analysis of glioma stem cells(GSCs) and non-GSCs
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ABSTRACT: To explore potential molecular mechanisms underlying the temporal process of DNA damage and repair in CSCs, we utilized deep RNA sequencing to analyze the expression of DNA damage and repair-associated genes at the transcriptome level. Our gene set analysis of CSCs and matched non-CSCs revealed a stemness-associated upward trend of global gene expression, particularly in NHEJ, mismatch excision repair (MMR) and HR pathways.
ORGANISM(S): Homo sapiens
PROVIDER: GSE108322 | GEO | 2017/12/20
SECONDARY ACCESSION(S): PRJNA423102
REPOSITORIES: GEO
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