Transcriptomics

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Expression data from isolated SHARPIN-deficient thymic Treg cells


ABSTRACT: One of the ubiquitin ligases, LUBAC, is a trimetric complex composed of SHARPIN, HOIL-1, and HOIP. LUBAC works at the proximal TCR signaling pathway allowing normal Treg development. We used microarrays to detail the global programme of gene expression underlying LUBAC-mediated signaling pathway in Treg cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE108793 | GEO | 2019/08/08

REPOSITORIES: GEO

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