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Expression data from mouse spleens after experimental stroke (reanalysis of dataset GSE70841 with additional experimental)

ABSTRACT: Infection is a major complication and cause of mortality and morbidity after acute stroke however the mechanisms are poorly understood. After experimental stroke the microarchitecture and cellular composition of the spleen are extensively disrupted resulting in deficits to immune function. We used microarray to determine differentially expressed genes in the spleens of mice after experimental stroke to determine contributers to immunosuppression after stroke.

ORGANISM(S): Mus musculus

PROVIDER: GSE108875 | GEO | 2018/06/06

REPOSITORIES: GEO

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Expression data from mouse spleens after experimental stroke

Project description:Infection is a major complication and cause of mortality and morbidity after acute stroke however the mechanisms are poorly understood. After experimental stroke the microarchitecture and cellular composition of the spleen are extensively disrupted resulting in deficits to immune function. We used microarray to determine differentially expressed genes in the spleens of mice after experimental stroke to determine contributers to immunosuppression after stroke.

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