Role of SUMOylation in differential ERα transcriptional repression by SERMs and pure antiestrogens in breast cancer cells
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ABSTRACT: RNA-seq: Gene expression profiling in MCF-7 cells treated with vehicle (0), estradiol (E2), the Selective ER Modulator 4-hydroxytamoxifen (OHT), or the pure antiestrogen fulvestrant (ICI). ChIP-seq: Genome-wide DNA binding profile of ERα and SUMO2/3 in MCF-7 cells treated with vehicle, E2 or ICI.
ORGANISM(S): Homo sapiens
PROVIDER: GSE108883 | GEO | 2018/01/09
SECONDARY ACCESSION(S): PRJNA429003
REPOSITORIES: GEO
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