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Genome-wide maps of histone modification and chromatin remodeler binding in acute myeloid leukemia blast cells and normal hematopoietic cells

ABSTRACT: We have used chromatin immunoprecipitation followed by high throughput sequencing to map regions of chromatin remodeler binding accompanied by histone modification state. We have used this data to distinguish between the transcriptional state of regulatory genes in leukemic and normal hematopoietic cells, and thus understand contribution of the chromatin remodeler towards leukemogenesis.

ORGANISM(S): Homo sapiens

PROVIDER: GSE108976 | GEO | 2018/01/10

SECONDARY ACCESSION(S): PRJNA429274

REPOSITORIES: GEO

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Genome-wide maps of chromatin remodeler binding in acute myeloid leukemia cell line.

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